Set in 1795, the film follows a band of Thugs led by Khudabaksh Azaad, who aspires to free Hindostan (the Indian subcontinent) from the rule of the expanding British East India Company. Alarmed, British commander John Clive sends a small-time Thug from Awadh, Firangi Mallah, to infiltrate and counter the threat

Thugs of Hindostan stars Aamir Khan, Amitabh Bachchan, and Fatima Sana Shaikh in the lead roles.